Our research interests focus on the regenerative potential of stem cells for treating a range of diseases. Life expectancy in Western society is continually improving but there is also a gradual increase in age-related health problems in these people. The decline in healthy physiological function makes us more susceptible to a wide variety of degenerative disorders that affect neurological, cardiovascular and musculoskeletal systems, to name a few.
Throughout the adult body, stem cell populations maintain and replenish local tissues. Our aim is to use these cells to restore function to diseased or damaged tissues. Research interests encompass two main themes:
The effects of the physical bioprocessing environment (including substrate composition, mechanical force and bioprocessing forces) on regenerative cell responses
Defining and exploiting adult stem cell niche signals for activation of therapeutic stem cell populations